
New Effort to Modernize America’s Nuclear Fuel Cycle and Support Advanced Reactor Deployment
WASHINGTON—The U.S. Department of Energy (DOE) today issued a Request for Information (RFI) inviting states to express interest in hosting Nuclear Lifecycle Innovation Campuses, a new effort to modernize the nation’s full nuclear fuel cycle and strengthen America’s leadership in advanced nuclear energy.
This action marks the first step towards potentially establishing voluntary Federal-State partnerships designed to advance regional economic growth, enhance national energy security, and build a coherent, end-to-end nuclear energy strategy for the country.
“Unleashing the next American nuclear renaissance will drive innovation, fuel economic growth, and create good-paying American jobs while delivering the affordable, reliable and secure energy America needs to power its future,” said U.S. Energy Secretary Chris Wright. “Nuclear Lifecycle Innovation Campuses give us the opportunity to work directly with states on regional priorities that support President Trump’s vision to revitalize America’s nuclear base.”
The proposed campuses could support activities across the full nuclear fuel lifecycle, including fuel fabrication, enrichment, reprocessing used nuclear fuel, and disposition of waste. Depending on state priorities and regional capabilities, the sites could also host advanced reactor deployment, power generation, advanced manufacturing, and co located data centers.
DOE is inviting states to provide clear statements of interest and constructive feedback on the structure of the Innovation Campuses. Submissions should outline state priorities—such as workforce development, infrastructure investment, economic diversification, or technology leadership— and describe the scope of activities the state envisions hosting. States are also encouraged to identify the funding structures, risk sharing approaches, incentives and federal partnerships required to successfully establish and sustain a full-cycle Innovation Campus.
Responses to the RFI are requested no later than April 1, 2026. Interested parties can learn more and respond at SAM.gov.
###













